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FLUOLEAD™

Pharmaceutical Business

4-tert-Butyl-2,6-dimethylphenylsulfur trifluoride
CAS:947725-04-4

Outline

FLUOLEAD is a novel nucleophilic fluorinating agent, that is crystalline solid (mp.66°C), and has enough stability against moisture to handle it in the open-air without fumes.

FLUOLEAD has excellent thermal stability up to 170°C (ARC method), so that it could be widely applicable to the numerous fluorinations, in particular for deoxtho-fluorination use, as an alternative of SF4 (Sulfur tetrafluoride) and DAST.

SF3
FLUOLEAD™
Protecting Group:Easil removed with trifloroacetic acid /Protecting Gropu Easily removed:After oxidized to sulfonate

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